The main goal of AID project is to improve clinical outcome, quality of life (QoL) and survival rate in breast cancer patients on adjuvant endocrine therapy with aromatase inhibitors (AI) by nutritional interventions. The 90 patients will receive either supplement or placebo pills (control group), or an anti-inflammatory diet for 4 months, along with the AI therapy. Changes in nutritional status (obesity, malnutrition, sarcopenia…), quality of life, biochemical and clinical parameters will be measured in comparison among three groups.

The second goal is to establish cause-and-effect relationships among the clinical outcomes, nutritional status and biochemical parameters related to cancer, including inflammatory and redox status, plasma lipidome and polymorphism of fatty acid desaturase (FADS) genes. Introducing an effective nutritional intervention in BRC patients as an integral part of the multimodal therapeutic approach through this project in all breast cancer patients in Serbia is our ultimate goal.